Supplements
The biological impact of supplements on aging, cognition, and physical performance. Molecular discoveries, hormone regulation, and the safety profiles of everyday essentials.
Essentials
videoSupplements and drugs most discussed for living longer
David Sinclair and Matthew LaPlante dive into various supplements and drugs believed to support longevity. Key substances include NAD boosters…
What Works
DHEA benefits are limited, and anti-aging proof is weak
DHEA is a real hormone precursor, and its level falls with age. But that does not prove oral DHEA improves aging, energy, muscle, or libido for most people. Human evidence supports a few narrower uses and raises real safety questions.
NMN and NR supplements raise blood NAD but have not slowed aging in humans
NMN and NR supplements reliably raise blood NAD, but human trials have not shown that they slow aging; measured benefits so far are small and inconsistent.
NAD supplements raise NAD in the body – health gains are not established yet
Nicotinamide adenine dinucleotide, or NAD, is a helper molecule that cells use for energy, DNA repair, and body clock control.…
Vitamin D may help cells age more slowly
Vitamin D may slow cellular aging by preserving telomere length, a new study finds. Learn about the benefits for DNA, proper dosage, and potential risks.
Low vitamin D and K levels tripled heart disease risk in one study
According to a doctor (A.M.) about another doctor (Résimont) about another doctor (Eric Müller) : IN PRACTICE: If deficient (<60):…
videoPractical ways to keep your brain sharp as you age
the molecular and lifestyle interventions to slow cognitive decline and diseases like Alzheimer’s. Key points include the importance of longevity…
Early Trials
New injectable drug CBL-514 may safely shrink belly fat by killing its cells
Scientists are testing a new injectable drug, CBL-514, that makes unwanted fat cells in a chosen body area self-destruct. Early…
Healing the liver to achieve sustainable weight loss without frustration by Dr. Réginald Allouche
According to Dr. Réginald Allouche, weight gain is not merely caused by overeating but by an overburdened liver that can…
Curcumin supplements may help prevent age-related macular degeneration
Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss in people over 50. A large U.S. electronic-health-record…
Sure Shot claims to reduce alcohol effects with clinically proven formulation
Sure Shot, formerly known as Safety Shot, is presented as the first clinically proven supplement to reduce blood alcohol levels…
videoTechnologies that could change how we age in the coming years
the rapid advancements in anti-aging medicine, emphasizing the potential of wearables, implantable devices, and biological age clocks to transform healthcare.…
videoThe latest approaches to slowing or reversing aging
Advanced medical interventions for longevity, including stem cell therapy, testosterone replacement, human growth hormone (HGH), and cellular reprogramming. While testosterone…