Supplements
The biological impact of supplements on aging, cognition, and physical performance. Molecular discoveries, hormone regulation, and the safety profiles of everyday essentials.
Essentials
videoSupplements and drugs most discussed for living longer
David Sinclair and Matthew LaPlante dive into various supplements and drugs believed to support longevity. Key substances include NAD boosters…
What Works
DHEA benefits are limited, and anti-aging proof is weak
DHEA is a real hormone precursor, and its level falls with age. But that does not prove oral DHEA improves aging, energy, muscle, or libido for most people. Human evidence supports a few narrower uses and raises real safety questions.
NMN and NR supplements raise blood NAD but have not slowed aging in humans
NMN and NR supplements reliably raise blood NAD, but human trials have not shown that they slow aging; measured benefits so far are small and inconsistent.
NAD supplements raise NAD in the body – health gains are not established yet
Nicotinamide adenine dinucleotide, or NAD, is a helper molecule that cells use for energy, DNA repair, and body clock control.…
Vitamin D may help cells age more slowly
Vitamin D may slow cellular aging by preserving telomere length, a new study finds. Learn about the benefits for DNA, proper dosage, and potential risks.
Low vitamin D and K levels tripled heart disease risk in one study
According to a doctor (A.M.) about another doctor (Résimont) about another doctor (Eric Müller) : IN PRACTICE: If deficient (<60):…
videoPractical ways to keep your brain sharp as you age
the molecular and lifestyle interventions to slow cognitive decline and diseases like Alzheimer’s. Key points include the importance of longevity…
Early Trials
Whole broccoli more effective for cancer prevention than supplements
Sulforaphane in broccoli found to target cancer stem cells Researchers at the University of Michigan discovered that sulforaphane, a compound…
Collagen supplements: more myth than miracle
Collagen-based supplements are often marketed as beneficial for skin, hair, and joint health, but scientific evidence supporting these claims is…
Blocking one protein extended mouse lifespan by 25%
Scientists have developed a promising anti-aging drug that has been shown to extend lifespan by up to 25% in lab…
Ashwagandha may ease stress and improve sleep, but it is not risk free
Ashwagandha is a plant used in Ayurvedic medicine. It is often called an adaptogen, meaning a substance that may help…
Longevity expert Peter Attia relies on 9 common supplements for heart health
Dr Peter Attia, a physician known for his book Outlive, recently listed the 9 supplements he takes each morning to…
A pill that mimics some effects of exercise is being tested in mice
A molecule called SLU-PP-332 boosted the metabolism and helped muscle gain and weight loss in mice – though it will…