Supplements
The biological impact of supplements on aging, cognition, and physical performance. Molecular discoveries, hormone regulation, and the safety profiles of everyday essentials.
Level 1
videoKey supplements and drugs for longevity and overall health improvement
David Sinclair and Matthew LaPlante dive into various supplements and drugs believed to support longevity. Key substances include NAD boosters…
Level 2
NAD supplements help cells produce energy (but anti-aging proof in humans is still limited)
NAD supplements like NMN and NR help cells produce energy and may fight aging. Learn how they work, what science says about their benefits, and the risks.
NAD supplements raise NAD in the body – health gains are not established yet
Nicotinamide adenine dinucleotide, or NAD, is a helper molecule that cells use for energy, DNA repair, and body clock control.…
Vitamin D may slow cellular aging by preserving telomeres, study finds
Vitamin D may slow cellular aging by preserving telomere length, a new study finds. Learn about the benefits for DNA, proper dosage, and potential risks.
Vitamin D and K deficiency: 3 times higher risk of cardiovascular events
According to a doctor (A.M.) about another doctor (Résimont) about another doctor (Eric Müller) : IN PRACTICE: If deficient (<60):…
videoEnhance brain health: strategies to slow brain aging and boost cognitive health
the molecular and lifestyle interventions to slow cognitive decline and diseases like Alzheimer’s. Key points include the importance of longevity…
videoReverse cosmetic aging: improve skin, nails, and hair health
Harvard professor David Sinclair and co-host Matthew LaPlante discuss methods to slow or reverse cosmetic aging, focusing on skin, hair,…
Level 3
Fish oil supplements may be worthless
Studies have shown that the omega-3 fatty acids found in fish such as salmon and mackerel provide health benefits, but…
Senolytic: a molecule that selectively kills senescent cells
Senolytics are a class of drugs designed to selectively eliminate senescent cells, which accumulate with age and contribute to aging-related…
Creatine supplement may help relieve some long COVID symptoms
Research shows that creatine has many benefits, including help improve strength and power, and support recovery between workouts. Creatine also appears to have a positive effect on some self-reported long COVID symptoms (but not physical fatigue). More research is needed.
NMN: current clinical trials point toward NMN safety
NMN is a molecule that may be useful in slowing down some aspects of aging. NMN is a precursor of NAD+.
NAD+ serves many critical functions in human cells, such as electron transport, cell signaling, and DNA repair, and is essential in processes like metabolism, cell death, aging, DNA repair, gene expression, or neuroinflammation.
Rapamycin may slow aging in animals and help older immune systems
Rapamycin is a credible anti aging candidate based on strong animal data and early human immune results, but it is not yet proven to extend human lifespan. More randomized trials in people are in progress.
Matcha can be healthy in small, unsweetened servings, say experts
Matcha is a safe, potentially beneficial drink when used in moderation and without added sugar, but its reputation still runs…