Aging
Research shows lifestyle is more important than genetics for lifespan and healthspan. Evidence-based ways to slow biological aging that improve daily life right away: more energy, better mood, deeper sleep, sharper focus, better health, and, through clearer thinking and steadier emotions, better relationships.
Level 1
People do not die of old age: aging weakens the body and disease causes death
A common phrase says someone “died of old age.” Medicine says otherwise. Doctors do not certify “old age” as a…
Plant protein and fish are linked with longer life, while red and processed meat raise risk
A recent media claim said that eating a lot of animal protein speeds aging. The idea has some truth, but…
Lifestyle counts far more than genetics for health and longevity
75-90 % of what determines human lifespan lies outside the DNA we inherit. That “environmental” portion is overwhelmingly shaped by lifestyle: medical care, nutrition, physical activity, smoking, social support, and more.
We create a false self in early life to meet external expectations and cope with childhood experiences – James Hollis
James Hollis explores the psychological and spiritual upheaval of midlife as a necessary and meaningful rite of passage. Drawing from…
Ultra-processed foods linked to weaker muscles and higher fat in thighs
A UCSF study finds eating ultra-processed foods adds fat to thigh muscles, making them weaker and raising arthritis risk, even if you exercise.
Walking like the most active people could add 5 to 11 years to life
A new study finds that matching the activity level of the top 25% of Americans could add 5 years to life expectancy, and up to 11 years for the inactive.
videoKey supplements and drugs for longevity and overall health improvement
David Sinclair and Matthew LaPlante dive into various supplements and drugs believed to support longevity. Key substances include NAD boosters…
videoWhat to eat and when to eat
Intermittent Fasting (IF): Eating within a restricted time window, like 16–20 hours of fasting daily, helps activate longevity pathways, reduce…
Lifting weights boosts brain function
Contrary to the stereotype of weightlifting being associated with brute strength, research shows that regular weight training can improve…
Level 2
videoReverse cosmetic aging: improve skin, nails, and hair health
Harvard professor David Sinclair and co-host Matthew LaPlante discuss methods to slow or reverse cosmetic aging, focusing on skin, hair,…
videoExercise, sauna and ice bath: exploring the health benefits of adversity mimetics, exercise, and temperature exposure
The importance of exercise and adversity mimetics in activating longevity pathways. David Sinclair explains how vigorous exercise, intermittent fasting, and…
videoAging is a controllable process that can be slowed and reversed
The podcast “Lifespan” by Dr. David Sinclair, a Harvard Medical School professor, explores the science of aging and how to…
The healthiest breakfast based on centenarian eating habits: whole-grain, plant proteins, fruits and vegetables
Research on centenarians’ diets suggests the world’s healthiest breakfast includes whole grains, such as oats, paired with plant-based proteins like…
Renting can accelerate aging more than obesity and smoking
Living as a tenant accelerates biological aging more than being obese, unemployed, or a former smoker, according to recent research.…
Alcohol consumption may affect future generations even before conception
New research suggests that alcohol consumption can impact the health of future generations, even before they are conceived. The study…
Level 3
For older adults, very long daily fasts were linked to higher heart death risk
Time restricted eating means limiting food to a set daily window, for example eating within 8 to 12 hours and…
Rapamycin may slow aging in animals and help older immune systems
Rapamycin is a credible anti aging candidate based on strong animal data and early human immune results, but it is not yet proven to extend human lifespan. More randomized trials in people are in progress.
Scientists slow aging in mice by restoring a brain protein called “menin” that declines with age
Scientists have pinpointed a single protein in the ventromedial hypothalamus, menin, that appears to act as a brake on the…
Brief deep red light may improve color vision in older adults
Scientists at University College London report that brief exposure to deep red light may partly restore age related vision losses,…
Sleep deprivation kills by damaging the gut, but antioxidants may help
Sleep deprivation kills flies and mice by causing oxidative damage in the gut, a process that antioxidants can reverse, according to a Harvard study.
Running is more efficient than walking, even 5min per day (2014)
Running as little as five minutes daily is associated with 30% lower all-cause mortality and 45% lower cardiovascular mortality compared to non-runners, according to a study tracking over 55,000 adults for 15 years.