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HSL helps maintain fat tissue from inside the nucleus

A Cell Metabolism study (first published online 23 October 2025) reports that hormone-sensitive lipase (HSL) is active on fat droplets and in fat-cell nuclei, where it helps maintain adipose tissue. In the mouse models and rare human HSL-deficiency cases described in the paper, the phenotype is lipodystrophy (abnormal loss or redistribution of fat tissue), not obesity. The work reframes how too much and too little functional fat tissue can both strain metabolism. It does not replace medical or lifestyle advice or prove any new treatment.

Frozen vegetables are a healthy choice

Frozen vegetables rival fresh produce on nutrients, price and safety Many shoppers assume that “fresh” automatically means “healthier,” yet freezing…