Supplements
The biological impact of supplements on aging, cognition, and physical performance. Molecular discoveries, hormone regulation, and the safety profiles of everyday essentials.
Level 1
videoSupplements and drugs most discussed for living longer
David Sinclair and Matthew LaPlante dive into various supplements and drugs believed to support longevity. Key substances include NAD boosters…
Level 2
Researcher favors fish oil, magnesium, and ashwagandha to support mood, stress control, and training
A clinical psychologist who studies supplements, Dr. Adrian Lopresti, says his own routine centers on three products chosen for mental…
Simple diet and lifestyle changes can lower your biological age
Supplements mentioned are: statins, vit D, zinc, fish oil and garlic.
A supplement safety researcher shares the three he actually takes
Dr. Bill Gurley has spent decades researching the safety of herbal supplements and takes three supplements a day: turmeric, tea…
NAD supplements: what they are, what they do
Clear guide to NAD supplements: what they are, how they work, key evidence, safety, and limits. Learn if NAD supplements help and what remains unproven.

Caffeine disrupts sleep even when taken 6 hours before bedtime
A study found that consuming 400 mg of caffeine (equivalent to approximately 3-4 cups of coffee, depending on size and type) even 6 hours before bedtime significantly disrupts sleep, reducing total sleep time by over an hour. Participants often underestimated these effects, with objective measures showing greater disruption than subjective reports. These findings support avoiding caffeine at least 6 hours before sleep.
Level 3
Sleep deprivation kills by damaging the gut, but antioxidants may help
Sleep deprivation kills flies and mice by causing oxidative damage in the gut, a process that antioxidants can reverse, according to a Harvard study.